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Demented versus non-demented very old inpatients: the same comorbidities but poorer functional and nutritional status

机译:老年痴呆症患者与非痴呆症患者:合并症相同,但功能和营养状况较差

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摘要

Background: demented patients have been reported to be healthier than other old people of the same age. Objectives: to assess comorbid conditions, functional and nutritional status in medically ill hospitalised patients with normal cognition or affected by dementia of various causes and severities, or mild cognitive impairment (MCI). Design and Setting: a prospective study was carried out, between January and December 2004, in the Rehabilitation and Geriatric Hospital (HOGER). Methods: activities of daily living (ADL), instrumental activities of daily living (IADL) and mini nutritional assessment (MNA) scores were assessed as a function of the status of the patient two weeks before admission to hospital. On admission, cognitive status was assessed by a systematic battery of neuropsychological tests, comorbid conditions were assessed with the Charlson comorbidity index (CCI), and body mass index (BMI) and functional independence measure (FIM) were determined. BMI and FIM were also determined on discharge. Results: we studied 349 patients (mean age 85.2±6.7; 76% women): 161 (46.1%) cognitively normal, 37 (10.6%) with MCI and 151 (43.3%) demented (61 Alzheimer's disease (AD), 62 mixed dementia (MD) and 17 vascular dementia (VaD)). ADL, IADL, FIM and MNA scores on admission decreased with cognitive status, regardless of the type of dementia. Functionality at discharge remained significantly lower in demented patients than in other patients. CCI was high and similar in all three groups (mean 4.6±2.7). Patients with VaD had poorer health than other demented patients, with a higher average comorbidity score, more frequent hypertension, stroke and hyperlipidaemia. Comorbidity did not increase with severity levels of dementia. Conclusions: in this cohort of very old inpatients, demented patients, non-demented patients and patients with MCI had similar levels of comorbidity, but demented patients had a poorer functional and nutritional status
机译:背景:据报导,痴呆症患者比同年龄的其他老年人更健康。目的:评估认知能力正常或患有各种原因和严重程度或轻度认知障碍(MCI)的痴呆症的住院医疗患者的合并症,功能和营养状况。设计与设置:前瞻性研究于2004年1月至12月在康复和老年医学医院(HOGER)进行。方法:在入院前两周,根据患者状况评估日常生活活动(ADL),日常生活工具活动(IADL)和小型营养评估(MNA)得分。入院时,通过系统的一系列神经心理学测试评估认知状态,并用查尔森合并症指数(CCI)评估合并症,并确定体重指数(BMI)和功能独立性指标(FIM)。出院时还确定了BMI和FIM。结果:我们研究了349名患者(平均年龄85.2±6.7;女性76%):认知正常的161名(46.1%),患有MCI的37名(10.6%)和患有痴呆(61名阿尔茨海默氏病(AD),混合型62名)的151名(43.3%)痴呆(MD)和17血管性痴呆(VaD))。不论痴呆类型如何,入院时的ADL,IADL,FIM和MNA分数随认知状态而降低。痴呆患者的出院功能仍显着低于其他患者。在所有三个组中,CCI很高且相似(平均4.6±2.7)。 VaD患者的健康状况较其他痴呆患者差,平均合并症评分更高,高血压,中风和高脂血症的发生频率更高。合并症并没有随着痴呆严重程度的增加而增加。结论:在这个非常老的住院患者队列中,痴呆患者,非痴呆患者和MCI患者的合并症水平相近,但痴呆患者的功能和营养状况较差

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